Body Composition injectableoral

AOD-9604

By Hack SmithLast updated: How we research

Burns fat without growth hormone effects

Common Uses
  • Fat Loss
  • Weight Loss Stalls
Evidence Grade
A — Strong — Human clinical trial data
Human randomized controlled trial data available.
Safety Notes

Phase 2 osteoarthritis trial completed; the program did not advance to Phase 3 — no completed Phase 3 OA trial exists Never received regulatory approval for any indication Listed on WADA prohibited substances list — banned in competitive sports Limited published human safety data despite Phase 2/3 trial history Black market products may contain contaminants or incorrect dosing

Mechanism of Action

AOD-9604 is a modified hGH C-terminal fragment (amino acids 176–191) with an N-terminal tyrosine addition, designed to retain the lipolytic (fat-burning) properties of hGH without its growth-promoting or diabetogenic effects. It appears to enhance lipolysis and increase energy expenditure through mechanisms that involve but do not solely depend on beta-3 adrenergic receptor activation, suggesting alternative or redundant pathways in fat metabolism. Key Pathways: Beta-3 adrenergic receptor signaling, Lipolysis and fat oxidation pathways, Energy expenditure regulation In obese animal models, AOD-9604 reduced body weight and fat mass while increasing fat oxidation and energy expenditure. These effects suggest potential utility for fat loss, though the translation of these findings to humans remains incompletely established despite early-phase clinical trials.

Common Dose Reference Ranges

Educational reference ranges only — discuss actual dosing with a qualified healthcare provider.

Low
250
mcg
Standard
375
mcg
High
500
mcg
🔬 Related compounds
AICARL-Carnitine
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Full AOD-9604 protocols — frequency, timing, cycle length, reconstitution & research

Frequency: Daily or every other day
Half-life: Estimated 30-60 minutes
Cycle length: 4 weeks
Side Effects
  • Injection site reactions
  • Headache
  • Nausea
Compatible Stacks
CJC-1295 (without DAC)IpamorelinBPC-157L-Carnitine
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