Guides & Learning Resources

In-depth, evidence-informed guides on peptides, hormones, nutrition, and research protocols.

All Guides

Compound deep-dives, protocols, nutrition, and more.

• GLP-1Health and Safety 8 min read
  GLP-1s and Vision Changes: What's Normal, What's Not, and the NAION Question
  Blurry or fluctuating vision on a GLP-1? Blood sugar and eyesight are directly linked - high or low. What's normal, what's a red flag, the NAION risk explained, and when to see your eye doctor.
• Compound Education 13 min read
  Growth Hormone Peptides Explained: CJC-1295, Ipamorelin, Tesamorelin
  How GH secretagogues actually work, why they're stacked in pairs, and how the main compounds compare.
• Compound Education 12 min read
  Mitochondrial Peptides Explained: SS-31, MOTS-C, NAD+ and More
  How the main mitochondrial peptides actually work, how they fit together, and the right order to think about them.
• Compound Education 14 min read
  Best Peptides for Autoimmune Conditions: An Evidence-Based Guide
  Which peptides actually have evidence for autoimmune conditions, honest evidence tiers, and which ones fit your specific situation.
• Health and Optimization 11 min read
  HRT and TRT Myths Debunked: What the Evidence Actually Says
  Does HRT cause cancer? Weight gain? Is it just for older people or only for men? Here's what the evidence actually says, for both men and women.
• Health and Optimization 9 min read
  Why Optimizing Your Hormones Might Be the Missing Piece
  Doing everything right and still stuck? Your hormones might be the missing piece, and checking them is more affordable than you think.
• Compound Education 9 min read
  Why Your GLP-1 Stopped Working: Understanding Plateaus
  Your GLP-1 probably didn't stop working. Here's what a plateau actually is and what your real options are.
• Compound Education 8 min read
  Why Does Retatrutide Make You Feel Hungrier? The Real Answer
  The real reason retatrutide can feel less suppressive after switching from another GLP-1, and what to do about it.
• Compound Education 9 min read
  Eloralintide Explained: The New Amylin Agonist for Weight Loss
  Eli Lilly's selective amylin agonist showing up to 20% weight loss — how it works and how it compares to GLP-1s.
• Nutrition 10 min read
  How Many Calories Should You Eat? TDEE Calculator and Macro Guide
  How to calculate your TDEE, set your calorie target, understand macros, and what changes when you're on a peptide protocol.
• BeginnerReconstitution 10 min read
  How to Reconstitute Peptides: The Complete Step by Step Guide
  Learn exactly how to reconstitute peptides correctly — BAC water volumes, storage, shelf life, and common mistakes. The complete beginner guide.
• BeginnerInjection Technique 10 min read
  How to Inject Peptides Subcutaneously: A Step-by-Step Guide
  Learn the correct subcutaneous injection technique for research peptides — equipment, injection sites, step-by-step process, common mistakes, and site rotation.
• BeginnerReconstitutionDosing 9 min read
  How Much BAC Water Do I Need? Reconstitution Math Explained
  Confused about how much bacteriostatic water to add to your peptide vial? This guide explains the concentration formula, dose volume math, and includes a quick-reference table.
• BeginnerStorage 9 min read
  How to Store Peptides Properly: Temperature, Light & Shelf Life
  The complete guide to peptide storage — lyophilized powder vs reconstituted solution, temperature ranges, what degrades peptides, and signs of degradation.
• ProtocolBeginnerCycling 11 min read
  Peptide Cycling 101: On/Off Cycles, Duration, and Why It Matters
  When and why to cycle peptides — receptor desensitization explained, cycling protocols for GH secretagogues, BPC-157, Epitalon, MK-677, and more.
• BeginnerPillar Guide 15 min read
  Beginner's Guide to Peptides: Everything You Need to Know to Start
  The complete beginner's guide to research peptides — what they are, delivery routes, how to choose by goal, equipment, the basic process, evidence grades, and safety basics.
• Supplements 14 min read
  The Essential Supplements That Actually Pair Well With Peptide Protocols
  The supplements that complement peptide protocols — why they work, how they interact, and what to look for. Includes electrolytes, aminos, NMN, magnesium, omega-3s, and more.
• Tools & GuidesCalculator 12 min read
  The Peptide Calculator: The Only One That Actually Solves the Right Problem
  A complete walkthrough of the BAC Water Optimizer, Standard Calculator, Reverse Calculator, and Blend modes — and what makes this tool different from every other peptide calculator.
• Supplements 8 min read
  Omega-3 Fish Oil and Peptides: Why This Supplement Actually Matters for Your Protocol
  Why omega-3s matter for healing, GLP-1, and cognitive peptide protocols — and what to look for in a quality product.
• Fat LossRecoveryGut HealthAnti-AgingCognition 8 min read
  Top 5 Peptides Most People Can Benefit From
  A practical breakdown of the five peptides that deliver the most value across fat loss, muscle, gut health, skin, and cognition — with dosing, who it's best for, and honest tips.
• Fat LossMuscleBody Composition 6 min read
  Bimagrumab + Semaglutide: The BELIEVE Trial Breakdown
  A breakdown of the Phase 2b BELIEVE trial — what bimagrumab is, how it works with semaglutide, and what the results actually mean for fat loss and muscle preservation.
• DopamineNeuroprotectionCognitive Enhancement 6 min read
  9-Methyl-β-Carboline (9-Me-BC)
  A research breakdown of 9-Me-BC — what it is, how it works, and why it's one of the more unusual compounds in the dopamine support space.
• GLP-1SemaglutideTirzepatideDosing 7 min read
  GLP-1 Split Dosing: Once-Weekly vs Twice-Weekly
  Once-weekly is the default — but not everyone responds the same way. A practical breakdown of why split dosing exists, who it helps, and how to know which approach fits you.
• GuideBeginner FriendlyCrypto 10 min read
  How to Pay with Crypto — Step by Step
  Never paid with crypto before? This beginner guide walks you through every method — wallet app, exchange, or checkout button. Plain English, no fluff.
• GuideBeginner FriendlyVendor Quality 9 min read
  How to Read a Peptide Certificate of Analysis (COA)
  What every number on a peptide COA actually means, which red flags to look for, and how to know when a vendor's test results are worth trusting.
• GuidePricingSourcing 8 min read
  How to Compare Peptide Prices — What to Actually Look For
  Price per mg is only part of the equation. A practical guide to comparing peptide costs, understanding vendor pricing structures, and avoiding false economy.
• GLP-1Fat LossComparisonSemaglutideTirzepatide 11 min read
  Semaglutide vs Tirzepatide: Which GLP-1 Is Right for You?
  A detailed comparison of semaglutide and tirzepatide — mechanism, dose, half-life, weight-loss data, and which to choose by goal. Based on Grade A+ clinical trial evidence.
• GLP-1Fat LossComparisonTirzepatideRetatrutide 11 min read
  Tirzepatide vs Retatrutide: Dual vs Triple Agonist
  Tirzepatide (FDA approved, Grade A+) vs retatrutide (Phase 2 complete, Grade C) — mechanism, weight-loss data, evidence gaps, and when the triple agonist is worth considering.
• HealingRecoveryBPC-157TB-500Comparison 11 min read
  BPC-157 vs TB-500: Which Healing Peptide Should You Use?
  BPC-157 and TB-500 compared on mechanism, evidence grade, dosing, and applications. Understand which suits your injury type, and why stacking both is the most common approach.
• GH SecretagoguesMuscle GrowthComparisonCJC-1295Ipamorelin 13 min read
  CJC-1295 vs Ipamorelin: Two Mechanisms, One Powerful Stack
  CJC-1295 (GHRH analog) and Ipamorelin (GHRP) work through different pituitary receptors. Learn how the stack works, which form of CJC-1295 to use, and when to prefer one over the other.
• GLP-1Fat LossComparisonOzempicMounjaro 10 min read
  Ozempic vs Mounjaro: What's the Actual Difference?
  Ozempic and Mounjaro are brand names for semaglutide and tirzepatide. This guide explains the brand name landscape, what each contains, how they compare, and which is prescribed for what.